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Testosterone is anabolic in nature, meaning it builds tissue. Therefore, if you create the right environment by eating a good diet and exercise regularly, you will be able to put on lean muscle. How long does testosterone take to work: timeline improved sex drive and better quality sleep the first two signs to look for is an improved sex drive and the ability to sleep better at night. The timeline of testosterone cypionate benefits provided here will give you a general idea of what to expect from your treatment. Please understand that each person responds to testosterone therapy in a unique way, just as a decline in testosterone affects each man in an individualized manner. Understanding how testosterone and estrogen operate in the body is helpful in order to make decisions about gender affirming hormone therapy. Discussing these options with your doctor is a great starting point if you are a transgender woman who is interested in hormonal therapy. Making your lab results look better is one thing — carefully balancing all of your hormones, managing potential side effects, and recommending other lifestyle changes, is where the art of medicine, and the skills of your chosen testosterone provider are critically important to the results you can expect to achieve from testosterone therapy. Testosterone replacement in men with low testosterone increases lean body mass and strength and decreases fat mass. Cardiovascular risk current evidence suggests that testosterone replacement in men is relatively safe in terms of cardiovascular health and does not cause important cardiovascular side effects. The following masculinizing effects can be expected as a result of testosterone therapy. These effects may take several months to be noticeable, and will continue to develop over a period of years. Thickening of the vocal chords and deepening of the voice; facial hair growth (mustache and/or beard growth). Changes in erections/ejaculations may require up to 6 months. Effects on quality of life manifest within 3-4 weeks, but maximum benefits take longer. Effects on depressive mood become detectable after 3-6 weeks with a maximum after 18-30 weeks. Effects on erythropoiesis are evident at 3 months, peaking at 9-12 months. With the fall in testosterone level, you may notice breast tenderness. The most other common side effects include increased urination, risk of high potassium and possibly lower blood pressure. Your provider will monitor your potassium levels. If these side effects are too significant, speak to your health care provider about alternatives. When testosterone levels are insufficiently suppressed by estradiol alone, antiandrogens can be used to suppress or block the effects of residual testosterone. Oral estradiol often has difficulty adequately suppressing testosterone levels, due to the relatively low estradiol levels achieved with it. The physical changes to my appearance (facial features, fat distribution, muscle distribution) were much, much slower – in fact, they kind of snuck up on me
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